Physiology of the Heart

Part One: STRUCTURE, BIOCHEMISTRY, AND BIOPHYSICS

1: Structure of the Heart and Cardiac Muscle

2: Energetics and Energy Production

3: Energy Utilization (Work and Heat)

4: The Contractile Proteins

5: The Cytoskeleton

6: Active State, Length-Tension Relationship, and Cardiac Mechanics

7: Excitation-Contraction Coupling: Extracellular and Intracellular Calcium Cycles

Part Two: SIGNAL TRANSDUCTION AND REGULATION

8: Signal Transduction: Functional Signaling

9: Signal Transduction: Proliferative Signaling

10: Regulation of Cardiac Muscle Performance: Functional and Proliferative Mechanisms

Part Three: NORMAL PHYSIOLOGY

11: The Heart as a Muscular Pump

12: The Working Heart

13: Cardiac Ion Channels

14: The Cardiac Action Potential

Part Four: CLINICAL PHYSIOLOGY

15: The Electrocardiogram

16: Arrhythmias

17: The Ischemic Heart

18: Heart Failure